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Workshop Programme

for period 9-12 August

Optimum Design for Mixed Effects Non-linear and Generalised Linear Models

9-12 August

Timetable

Tuesday 09 August
09:00-09:25 Registration DAE
09:25-09:30 Opening remarks and welcome from John Toland (INI Director Designate) DAE
Chair: B. Bogacka
09:30-10:30 Bates, D (Wisconsin-Madison) DAE
  Lecture on modelling: Mixed effects non-linear and generalized linear models Sem 1
10:30-11:00 Morning coffee DAE
Chair: E. Demidenko
11:00-11:45 Schwabe, R (Otto Von Guericke) DAE
  "To estimate or to predict" - implications on the design for linear mixed models Sem 1
11:45-12:30 Donev, A; Loeza-Serrano, S (Manchester) DAE
  Experimental designs for estimating variance components Sem 1
12:30-13:30 Lunch at Wolfson Court DAE
Chair: A. Donev
14:00-14:45 Gilmour, S (Southampton) DAE
  GLMs and GLMMs in the analysis of randomized experiments Sem 1
14:45-15:30 Woods, D (Southampton) DAE
  Block designs for non-normal data via conditional and marginal models Sem 1
15:30-16:00 Afternoon tea DAE
Chair: S. Gilmour
16:00-16:45 Waite, T (Southampton) DAE
  Designs for mixed models with binary response Sem 1
16:45-17:30 Welcome wine reception DAE
Wednesday 10 August
Chair: S. Leonov
09:30-10:30 Demidenko, E (Dartmouth College) DAE
  Lecture on estimation and inference: Non-maximum likelihood estimation and statistical inference for linear and nonlinear mixed models Sem 1
10:30-11:00 Morning coffee DAE
Chair: D. Woods
11:00-11:45 Ueckert, S (Uppsala) DAE
  Optimal design of clinical trials in Alzheimer's disease Sem 1
11:45-12:30 Mentré, F (Paris) DAE
  Optimal designs for pharmacokinetic and viral dynamic nonlinear mixed effect models in HIV treatment Sem 1
12:30-13:30 Lunch at Wolfson Court DAE
Chair: D. Bates
14:00-14:45 Rosner, G (Johns Hopkins) DAE
  Bayesian enrichment strategies for randomized discontinuation trials Sem 1
14:45-15:30 Mueller, P (Texas at Austin) DAE
  Sequential stopping for high-throughput experiments Sem 1
15:30-16:00 Afternoon tea DAE
16:00-17:30 Poster storm and Posters DAE
16:00-16:30 Bates, D (Wisconsin) DAE
  Profiling the deviance to assess variability of parameter estimates in mixed models Sem 1
Thursday 11 August
Chair: P. Mueller
09:30-10:30 Fedorov, V (GlaxoSmithKline) DAE
  Mixed models: design of experiments Sem 1
10:30-11:00 Morning coffee DAE
Chair: G. Rosner
11:00-11:45 Patan, M (Zielona Gora, Poland) DAE
  Group sensor scheduling for parameter estimation of random-effects distributed systems Sem 1
11:45-12:30 Latif, M (Dhaka, Bangladesh) DAE
  Optimum designs for transform-both-sides nonlinear mixed effects model in the presence of covariates Sem 1
12:30-13:30 Lunch at Wolfson Court DAE
14:00-17:30 Cambridge Colleges Tour DAE
19:00-22:00 Conference dinner at Peterhouse DAE
Friday 12 August
09:30-09:45 Intro by B Bogacka and S Leonov DAE
Chair: B. Bogacka
Session: Population Optimum Design of Experiments
09:45-10:30 Leonov, S (Vertex) DAE
  Approximation of the individual Fisher information matrix and its use in design of population PK/PD studies Sem 1
10:30-11:00 Morning coffee DAE
Chair: S. Leonov
11:00-11:45 Mielke, T (Otto-von-Guericke) DAE
  Approximation of the Fisher information and design in nonlinear mixed effects models Sem 1
11:45-12:30 Nyberg, J (Uppsala) DAE
  Improved conditional approximations of the population Fisher information matrix Sem 1
12:30-13:30 Lunch at Wolfson Court DAE
Chair: V. Federov
14:00-14:45 Waterhouse, T (Eli Lilly & Company) DAE
  Experiences in optimal design for population PK/PD models Sem 1
14:45-15:30 Duffull, S (Otago) DAE
  A general method to determine sampling windows for nonlinear mixed effects models Sem 1
15:30-16:00 Afternoon tea DAE
Chair: S. Duffull
16:00-16:30 Mentré, F (Paris) DAE
  Software for the population optimum design of experiments Sem 1
16:30-17:00 Discussion DAE
Other Seminars
Seminars in the University
National and International Scientific Research Meetings

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