Workshop Programme
for period 9-12 August
Optimum Design for Mixed Effects Non-linear and Generalised Linear Models
9-12 August
Timetable
| Tuesday 09 August | ||
| 09:00-09:25 | Registration | DAE |
| 09:25-09:30 | Opening remarks and welcome from John Toland (INI Director Designate) | DAE |
| Chair: B. Bogacka | ||
| 09:30-10:30 | Bates, D (Wisconsin-Madison) | DAE |
| Lecture on modelling: Mixed effects non-linear and generalized linear models | Sem 1 | |
| 10:30-11:00 | Morning coffee | DAE |
| Chair: E. Demidenko | ||
| 11:00-11:45 | Schwabe, R (Otto Von Guericke) | DAE |
| "To estimate or to predict" - implications on the design for linear mixed models | Sem 1 | |
| 11:45-12:30 | Donev, A; Loeza-Serrano, S (Manchester) | DAE |
| Experimental designs for estimating variance components | Sem 1 | |
| 12:30-13:30 | Lunch at Wolfson Court | DAE |
| Chair: A. Donev | ||
| 14:00-14:45 | Gilmour, S (Southampton) | DAE |
| GLMs and GLMMs in the analysis of randomized experiments | Sem 1 | |
| 14:45-15:30 | Woods, D (Southampton) | DAE |
| Block designs for non-normal data via conditional and marginal models | Sem 1 | |
| 15:30-16:00 | Afternoon tea | DAE |
| Chair: S. Gilmour | ||
| 16:00-16:45 | Waite, T (Southampton) | DAE |
| Designs for mixed models with binary response | Sem 1 | |
| 16:45-17:30 | Welcome wine reception | DAE |
| Wednesday 10 August | ||
| Chair: S. Leonov | ||
| 09:30-10:30 | Demidenko, E (Dartmouth College) | DAE |
| Lecture on estimation and inference: Non-maximum likelihood estimation and statistical inference for linear and nonlinear mixed models | Sem 1 | |
| 10:30-11:00 | Morning coffee | DAE |
| Chair: D. Woods | ||
| 11:00-11:45 | Ueckert, S (Uppsala) | DAE |
| Optimal design of clinical trials in Alzheimer's disease | Sem 1 | |
| 11:45-12:30 | Mentré, F (Paris) | DAE |
| Optimal designs for pharmacokinetic and viral dynamic nonlinear mixed effect models in HIV treatment | Sem 1 | |
| 12:30-13:30 | Lunch at Wolfson Court | DAE |
| Chair: D. Bates | ||
| 14:00-14:45 | Rosner, G (Johns Hopkins) | DAE |
| Bayesian enrichment strategies for randomized discontinuation trials | Sem 1 | |
| 14:45-15:30 | Mueller, P (Texas at Austin) | DAE |
| Sequential stopping for high-throughput experiments | Sem 1 | |
| 15:30-16:00 | Afternoon tea | DAE |
| 16:00-17:30 | Poster storm and Posters | DAE |
| 16:00-16:30 | Bates, D (Wisconsin) | DAE |
| Profiling the deviance to assess variability of parameter estimates in mixed models | Sem 1 | |
| Thursday 11 August | ||
| Chair: P. Mueller | ||
| 09:30-10:30 | Fedorov, V (GlaxoSmithKline) | DAE |
| Mixed models: design of experiments | Sem 1 | |
| 10:30-11:00 | Morning coffee | DAE |
| Chair: G. Rosner | ||
| 11:00-11:45 | Patan, M (Zielona Gora, Poland) | DAE |
| Group sensor scheduling for parameter estimation of random-effects distributed systems | Sem 1 | |
| 11:45-12:30 | Latif, M (Dhaka, Bangladesh) | DAE |
| Optimum designs for transform-both-sides nonlinear mixed effects model in the presence of covariates | Sem 1 | |
| 12:30-13:30 | Lunch at Wolfson Court | DAE |
| 14:00-17:30 | Cambridge Colleges Tour | DAE |
| 19:00-22:00 | Conference dinner at Peterhouse | DAE |
| Friday 12 August | ||
| 09:30-09:45 | Intro by B Bogacka and S Leonov | DAE |
| Chair: B. Bogacka | ||
| Session: Population Optimum Design of Experiments | ||
| 09:45-10:30 | Leonov, S (Vertex) | DAE |
| Approximation of the individual Fisher information matrix and its use in design of population PK/PD studies | Sem 1 | |
| 10:30-11:00 | Morning coffee | DAE |
| Chair: S. Leonov | ||
| 11:00-11:45 | Mielke, T (Otto-von-Guericke) | DAE |
| Approximation of the Fisher information and design in nonlinear mixed effects models | Sem 1 | |
| 11:45-12:30 | Nyberg, J (Uppsala) | DAE |
| Improved conditional approximations of the population Fisher information matrix | Sem 1 | |
| 12:30-13:30 | Lunch at Wolfson Court | DAE |
| Chair: V. Federov | ||
| 14:00-14:45 | Waterhouse, T (Eli Lilly & Company) | DAE |
| Experiences in optimal design for population PK/PD models | Sem 1 | |
| 14:45-15:30 | Duffull, S (Otago) | DAE |
| A general method to determine sampling windows for nonlinear mixed effects models | Sem 1 | |
| 15:30-16:00 | Afternoon tea | DAE |
| Chair: S. Duffull | ||
| 16:00-16:30 | Mentré, F (Paris) | DAE |
| Software for the population optimum design of experiments | Sem 1 | |
| 16:30-17:00 | Discussion | DAE |
| Other Seminars |
|
Seminars in the University National and International Scientific Research Meetings |