An Isaac Newton Institute Workshop

Theory and Applications of Coupled Cell Networks

On the repressilator

Authors: Josef Hofbauer (UCL), St. Mueller, P. Schuster (Theoretical Biochemistry Group, University of Vienna)

Abstract

The repressilator is a simple gene regulatory network consisting of a loop of three proteins that repress the transcription of the following gene. Such a synthetic network was constructed by Elowitz and Leibler (2000) in E.coli and shown to oscillate. We propose a new dynamic model for this gene network and analyse its dynamic features.