An Isaac Newton Institute Workshop

Recent Advances in Statistical Genetics and Bioinformatics

Detecting Selection from Population Genetic Data

14th December 2006

Authors: Rasmus Nielsen (University of Copenhagen), Carlos D. Bustamante (), Scott Williamson (), Melissa Hubisz (), Andrew G. Clark ()

Abstract

We will present an analysis of several large scale human populaiton genetic data sets. We use a combination of simulation and analytical approaches to identify genes and genomic regions targeted by Darwinian selection. The biological implications of some of the results are discussed.