SMC Seminar List
for period 19 Jan to 9 Jul
| Tuesday 20 January | ||
| 09.00-10.00 | Croquette, V (CNRS) | |
| Single molecule study of DNA/protein interactions. | Sem 1 | |
| 10.00-11.00 | Finkelstein, A (IPR, Russia) | |
| Two bottlenecks for ab initio prediction of protein structures | Sem 1 | |
| 11:30-12:30 | Thornton, J (EBI, Cambridge) | |
| Protein solubility and evolution | Sem 1 | |
| 14.00-15.00 | Trinick, J (Leeds) | |
| Linear molecular motors | Sem 1 | |
| 15.30-16.30 | Fisher, ME (Maryland) | |
| Theory for molecular motors: may be predictive? | Sem 1 | |
| 17.15-18.00 | Goodfellow, J (BBSRC) | |
| Towards a predictive biology | Sem 2 | |
| Wednesday 21 January | ||
| 09.00-10.00 | Ogunnaike, B (Delaware) | |
| Cellular modelling of cancer - do we have the tools? | Sem 1 | |
| 10.00-11.00 | Bray, D (Cambridge) | |
| Intracellular signalling in a molecular jungle: insights from bacterial chemotaxis | Sem 1 | |
| 11.30-12.30 | Leibler, S (Rockefeller) | |
| Genetic and biochemical networks: a physicist's perspective | Sem 1 | |
| 14.00-15.00 | Nelson, P (Pennsylvania) | |
| Integrating biological physics into the undergraduate curriculum: the US National Academy report and beyond | Sem 1 | |
| 15.30-16.30 | Hansen, J-P (Cambridge) | |
| Simple models for ion channels: selectivity, intermittency and ion transport | Sem 1 | |
| Thursday 22 January | ||
| 09:00-10:00 | Dill, K (UCSF) | |
| Protein folding kinetics: some new twists on the transition state idea | Sem 1 | |
| 10.00-11.00 | Frenkel, D (Amsterdam) | |
| Random design: a litany of ignorance | Sem 1 | |
| 11.30-12.30 | Durbin, R (Sanger, Cambridge) | |
| Genomic data and prediction: the value of comprehensive information | Sem 1 | |
| Friday 23 January | ||
| 09.00-10.00 | Townsend, R (Royal Society of Chemistry) | |
| The roles of the chemical sciences in predictive biology | Sem 1 | |
| 10:00-11:00 | Templer, R (Imperial) | |
| Who cares about lipids anyway? | Sem 1 | |
| 11:30-12:30 | Walker, J (Cambridge) | |
| Rotary motors | Sem 1 | |
| Tuesday 27 January | ||
| 09:30-10:30 | Levine, A (Massachusettes) | |
| The worm turns: the Helix-Coil wormlike chain | Sem 1 | |
| Thursday 29 January | ||
| 09:30-10:30 | Dryden, DTF (Edinburgh) | |
| Type I DNA restriction enzymes: smart molecular machines | Sem 1 | |
| Tuesday 03 February | ||
| 11:30-12:30 | Martin, P (Institut Curie, Paris) | |
| How the ear listens: spontaneous mechanical oscillations by mechanosensory hair cells | Sem 1 | |
| Thursday 05 February | ||
| 11:30-12:30 | Ou-Yang, Z-C (Beijing) | |
| Elastic theory of a single DNA molecule | Sem 1 | |
| Monday 09 February | ||
| 11:30-13:00 | Komura, S (Tokyo Metropolitan) | |
| Phase separation in biomembranes | Sem 2 | |
| Tuesday 10 February | ||
| 11:30-13:00 | Flyvbjerg, H (Riso National Lab) | |
| Informal discussion: Signal processing/interpretation issues in optical tweezers and AFM cantilevers | Sem 2 | |
| Wednesday 11 February | ||
| 11:30-13:00 | Juelicher, F (MPI Complex Systems, Dresden) | |
| Active gels and cytoskeletal dynamics | Sem 2 | |
| Tuesday 17 February | ||
| 11:30-12:30 | Baumgaertner, A (Juelich) | |
| In silico studies of cell motility | Sem 1 | |
| Wednesday 18 February | ||
| 11:30-12:30 | Carlon, E (Lille) | |
| Melting of double-stranded DNA-theory and experiments | Sem 1 | |
| Thursday 19 February | ||
| 11:30-12:30 | Mohammad-Rafiee, F (Zanjan) | |
| Probing chromatin dynamics with synthetic DNA ligands | Sem 1 | |
| Tuesday 24 February | ||
| 11:30-12:30 | Andelman, D (Tel Aviv) | |
| The onset of complexation of polymers and DNA with amphiphiles | Sem 1 | |
| Wednesday 25 February | ||
| 11:30-12:30 | Tanaka, S (Edinburgh) | |
| Crystallization and diffusion of globular proteins in lipid cubic phases | Sem 1 | |
| Thursday 26 February | ||
| 11:30-12:30 | Vilfan, A (J Stefan Institute) | |
| Elastic lever-arm model for myosin V | Sem 1 | |
| Tuesday 02 March | ||
| 11:30-12:30 | Liverpool, T (Leeds) | |
| Dynamics of active filament solutions | Sem 1 | |
| 14:00-15:00 | Lukatsky, D (Amsterdam) | |
| Membrane fusion | Sem 1 | |
| Thursday 04 March | ||
| 11:30-12:30 | Head, D (Amsterdam) | |
| The deformations and Green's response of cross-linked biopolymer networks | Sem 1 | |
| Monday 08 March | ||
| 17.00-17.15 | Kingman, J, McLeish, T | |
| Welcome | Sem 1 | |
| Tuesday 09 March | ||
| 11:00-12:00 | Travers, A, Poon, W (Cambridge, Edinburgh) | |
| Workshop on histone complexation in chromatin | Sem 1 | |
| Wednesday 10 March | ||
| 11:30-12:30 | Trinick, J (Leeds) | |
| Structural studies of the giant protein titin | Sem 1 | |
| 14:00-15:00 | Hawkins, R (Leeds) | |
| Entropic allostery in proteins | Sem 1 | |
| Thursday 11 March | ||
| 11:30-12:30 | Golestanian, R (Zanjan) | |
| Orientational ordering of rod-like polyelectrolytes | Sem 1 | |
| Monday 15 March | ||
| 14:00-14:15 | ||
| Introduction | Sem 1 | |
| 14:15-15:00 | Fersht, A (Cambridge) | |
| Realistic \& predictive simulation? | Sem 1 | |
| 15:00-16:00 | ||
| Discussion Chair: T McLeish | Sem 1 | |
| 16:30-17:30 | ||
| Resumed plenary or informal discussions | Sem 1 | |
| Tuesday 16 March | ||
| 09:00-10:00 | McLeish, T, Wales, D (Leeds, Cambridge) | |
| Features of high dimensional searches | Sem 1 | |
| 10:00-11:00 | ||
| Discussion Chair: H Roder | Sem 1 | |
| 11:30-12:30 | ||
| Resumed plenary or informal discussions | Sem 1 | |
| 14:00-15:00 | Shakhnovich, E, Thirumalai, D (Harvard, Maryland) | |
| Course-grained view of transition state ensembles | Sem 1 | |
| 15:00-16:00 | ||
| Discussion Chair: A Finkelstein | Sem 1 | |
| 16:30-17:30 | ||
| Resumed plenary or informal discussions | Sem 1 | |
| Wednesday 17 March | ||
| 09:00-10:00 | Vendruscolo, M, Paci, E (Cambridge, Zurich) | |
| Fine-grained simulation of transition state ensembles | Sem 1 | |
| 10:00-11:00 | ||
| Discussion Chair: C Dobson | Sem 1 | |
| 11:30-12:30 | ||
| Resumed plenary or informal discussions | Sem 1 | |
| 14:00-15:00 | Fernandez, J, Williams, P (Columbia, Nottingham) | |
| Mechanical folding \& unfolding | Sem 1 | |
| 15:00-16:00 | ||
| Discussion Chair: J Clark | Sem 1 | |
| 16:30-17:30 | ||
| Resumed plenary or informal discussions | Sem 1 | |
| Thursday 18 March | ||
| 09:00-10:00 | Oliveberg, M, Radford, S (Umea, Leeds) | |
| Dynamics of energy landscapes | Sem 1 | |
| 10:00-11:00 | ||
| Discussion Chair: JE Shea | Sem 1 | |
| 11:30-12:30 | ||
| Resumed plenary or informal discussions | Sem 1 | |
| 14:00-15:00 | Kiefhaber, T, Eaton, W (Basel, NIH Maryland) | |
| Early events in protein folding | Sem 1 | |
| 15:00-16:00 | ||
| Discussion Chair: A Fersht | Sem 1 | |
| 16:30-17:30 | ||
| Resumed plenary or informal discussions | Sem 1 | |
| Friday 19 March | ||
| 09:00-10:00 | Dobson, C (Cambridge) | |
| Review \& summing-up | Sem 1 | |
| 10:00-11:00 | ||
| Discussion Chair: SE Radford | Sem 1 | |
| Tuesday 23 March | ||
| 10:30-12:30 | ||
| First Scientific Session - Theories of Processive Motors Chair: Robert A Cross | Sem 2 | |
| 13:30-15:30 | ||
| Second Scientific Session - Experimental Findings Chair: Thomas AJ Duke | Sem 2 | |
| 16:00-17:30 | ||
| Discussion Sessions - breakout groups (theorist \& experimentalist mixed) | DS | |
| 17:30-18:00 | ||
| Reports from breakout sessions | Sem 1 | |
| Wednesday 24 March | ||
| 09:00-10:30 | ||
| Third Scientific Session - Cellular Mechanisms Chair: Justin E Molloy | Sem 1 | |
| 11:00-12:00 | ||
| Breakout groups (theory \& experimental mixed) | Sem 1 | |
| 12:00-12:30 | ||
| Reports from breakout groups | Sem 1 | |
| 13:30-15:30 | ||
| Self-assembled-sessions Detailed discussion of experiment / theory development | Sem 1 | |
| Wednesday 14 April | ||
| 11:30-12:30 | Mahadevan, L (Harvard) | |
| Statics and dynamics of actin assemblies | Sem 1 | |
| Thursday 15 April | ||
| 11:30-12:30 | Smith, J (Heidelberg) | |
| Protein dynamics and function | Sem 1 | |
| Tuesday 20 April | ||
| 11:30-12:30 | Ben-Jacob, E (Tel-Aviv ) | |
| Why bacteria go complex: higher flexibility for better adaptability | Sem 1 | |
| Wednesday 21 April | ||
| 11:00-12:00 | Srivastava, V (Cavendish Laboratory) | |
| The statistical mechanics of brain storage | Sem 1 | |
| Thursday 22 April | ||
| 11:30-12:30 | Maggs, T (ESPCI, Paris) | |
| Simulating the Ether: local algoritms for long-ranged forces | Sem 1 | |
| 15:00-16:00 | Baruchi, I (Tel Aviv) | |
| Functional holography of correlations matrices for biological networks | Sem 1 | |
| Monday 26 April | ||
| 12:00-12:15 | Taylor, WR (NIMR) | |
| Introduction | Sem 1 | |
| 12:15-13:00 | Sasidharan, RK, Chothia, C (Cambridge) | |
| Structural constraints on protein mutations | Sem 1 | |
| 13:45-14:30 | Recio, JF (Cambridge) | |
| Protein-protein docking by global energy optimisation | Sem 1 | |
| 14:30-15:30 | Abeln, S (Oxford) | |
| Fold usage on genomes \& protein structure evolution | Sem 1 | |
| Tuesday 27 April | ||
| 10:00-10:15 | ||
| Modelling / MD: Introduction | Sem 1 | |
| 10:15-11:00 | Mizuguchi, K (Cambridge) | |
| Sequence-structure homology recognition | Sem 1 | |
| 11:30-12:30 | Fraternali, F (NIMR) | |
| Modelling solvent forces | Sem 1 | |
| 13:30-14:30 | Vendruscolo, M (Cambridge) | |
| Determination of partially folded states of proteins at atomic resolution | Sem 1 | |
| 14:30-15:30 | Saldanha, J (NIMR) | |
| Modelling and drug design | Sem 1 | |
| 16:00-17:00 | Watson, J (EBI, Cambridge) | |
| Case studies in assigning function from structure in structural genomics | Sem 1 | |
| Wednesday 28 April | ||
| 10:00-10:15 | ||
| Ab initio / folding design: Introduction | Sem 1 | |
| 10:15-11:00 | Burke, D (Cambridge) | |
| Ab initio modelling | Sem 1 | |
| 11:30-12:30 | Taylor, WR (NIMR) | |
| Folds, knots and tangles | Sem 1 | |
| 13:30-14:30 | Chelliah, V (Cambridge) | |
| Identification of interacting sites in protein families | Sem 1 | |
| 14:30-15:30 | de Pristo, M (Cambridge) | |
| Rapper | Sem 1 | |
| 16:00-17:00 | Madera, M (Cambridge) | |
| Comparisons of sequence profiles | Sem 1 | |
| 17:00-18:00 | Jones, D (UCL) | |
| Prediction of native disorder in proteins | Sem 1 | |
| Thursday 29 April | ||
| 10:00-10:15 | ||
| Evolution: Introduction | Sem 1 | |
| 10:15-11:00 | Blackburne, B (NIMR) | |
| Minimalist protein models and evolution | Sem 1 | |
| 11:30-12:30 | Goldstein, R (NIMR) | |
| Modelling molecular evolution: Gprotein Coupled Receptors | Sem 1 | |
| 13:30-14:30 | Shanahan, H (NIMR) | |
| DNA binding sites | Sem 1 | |
| 14:30-15:30 | Calladine, C (Cambridge) | |
| Mechanics of interfaces in alpha-helical super-coils | Sem 1 | |
| Tuesday 04 May | ||
| 14:30-15:30 | Flyvbjerg, H (Copenhagen) | |
| Kinetics of self-assembling microtubules: an ``inverse problem" in biochemistry | Sem 1 | |
| Wednesday 05 May | ||
| 11:30-12:30 | Flyvberg, H (Copenhagen) | |
| Cell motility as persistent random motion-``revisited" | Sem 1 | |
| Thursday 06 May | ||
| 11:00-13:00 | Mayor, S, Rao, M (Bangalore) | |
| Dynamics of intracellular membrane traffic: interacting active networks | Sem 1 | |
| Tuesday 11 May | ||
| 11:30-12:30 | Colby, RH (Penn State) | |
| Reversible aggregation of albumin | Sem 1 | |
| Wednesday 12 May | ||
| 11:30-12:30 | Baumgaertner, A (Juelich) | |
| A simulation of membrane proteins | Sem 1 | |
| Thursday 13 May | ||
| 11:30-12:30 | Frischknecht, A (Sandia) | |
| Molecular theory of lipid bilayers | Sem 1 | |
| Monday 17 May | ||
| 16:00-17:00 | Egelhaaf, S (Edinburgh) | |
| Micelle-vesicle transitions in lecithin-bile salt mixtures | Sem 2 | |
| Tuesday 18 May | ||
| 11:30-12:30 | Mogilner, A (Davis) | |
| Self-organisation of microtubule asters | Sem 2 | |
| Wednesday 19 May | ||
| 09:30-11:00 | Harder, T (Oxford) | |
| From nano-scale cluster to functional platform: lipid raft domains in cell membranes | Sem 2 | |
| 11:30-13:00 | Keller, S (Washington) | |
| Immiscible liquid phases in lipid membranes containing cholesterol | Sem 2 | |
| 14:00-15:30 | Beales, P, Gordon, V (Edinburgh) | |
| Phase separation in binary lipid vesicles | Sem 2 | |
| 16:00-17:30 | Lipowsky, R (Potsdam) | |
| Domains in membranes and vesicles | Sem 2 | |
| Thursday 20 May | ||
| 09:30-11:00 | Olmsted, P (Leeds) | |
| Shape transformations in phase separated membranes | Sem 2 | |
| 11:30-13:00 | Mayor, S, Rao, M (Bangalore) | |
| Active lipid-based organisation on living cell surfaces | Sem 2 | |
| 14:00-15:30 | Sens, P (Paris) | |
| Modelling lipid rafts: size, shape, and possible involvement in membrane mechano-sensitivity | Sem 2 | |
| 16:00-17:30 | ||
| Round-table discussion | Sem 2 | |
| Friday 21 May | ||
| 11:30-12:30 | Chan, HS (Toronto) | |
| Cooperativity principles in protein folding: experimental criteria and interacition nonadditivity | Sem 2 | |
| Tuesday 25 May | ||
| 11:30-12:30 | Potemkin, II (Moscow) | |
| Adsorbed comb-like copolymers as a tool for molecular walkers | Sem 1 | |
| Thursday 27 May | ||
| 11:30-12:30 | Odde, D (Minesota) | |
| Modeling microtubule self-assembly dynamics during mitosis | Sem 1 | |
| Wednesday 02 June | ||
| 09:30-16:00 | Bray, D, Conway Morris, S, Laughlin, S (McLeish,T Poon,W) | |
| Thinking about evolution in physics and biology | Sem 1 | |
| Thursday 03 June | ||
| 11:30-12:30 | Sear, R (Surrey) | |
| Highly specific protein-protein interactions, evolution and negative design | Sem 1 | |
| Tuesday 08 June | ||
| 11:30-12:30 | Howard, M (Imperial College) | |
| Models for precise protein localisation in bacteria | Sem 1 | |
| Monday 21 June | ||
| 13:30-14:30 | Dobson, CM (Cambridge) | |
| Protein interactions in the context of folding, misfolding \& aggregation | Sem 1 | |
| 14:30-15:30 | Fink, AL (California) | |
| Factors affecting the aggregation of the natively unfolded protein alpha-synuclein | Sem 1 | |
| 16:00-17:00 | Minton, AP (NIH) | |
| Mesoscopic models for the effect of macromolecular crowding, macromolecular confinement \& surface adsorption upon protein assoc. | Sem 1 | |
| Tuesday 22 June | ||
| 09:00-10:00 | Thornton, JM (European Bioinformatics Inst.) | |
| Protein-protein interactions from a structural perspective | Sem 1 | |
| 10:00-11:00 | Deem, MW (Rice) | |
| Random energy models for interactions and dynamics in the immune response to viruses, vaccines, and cancer | Sem 1 | |
| 11:30-12:30 | Teichmann, SA (Cambridge) | |
| Domain interactions in multi-domain proteins | Sem 1 | |
| 14:00-15:00 | Janin, J (CNRS) | |
| A structural basis for the specificity of protein-protein recognition | Sem 1 | |
| 16:00-17:00 | Truskett, TM (Texas, Austin) | |
| Towards a simple coarse-grained strategy for modelling unfolding, phase separation, and aggregation in protein solutions | Sem 1 | |
| Wednesday 23 June | ||
| 09:00-10:00 | Harden, JL (Johns Hopkins) | |
| Sequence patterning in simple de novo proteins with tailored association behavior | Sem 1 | |
| 10:00-11:00 | Vekilov, PG (Houston) | |
| Phase transitions in protein solutions | Sem 1 | |
| 11:15-12:15 | Pearl, L (Institute of Cancer Research) | |
| Achieving specificity in regulated protein-protein interactions | Sem 1 | |
| 14:00-15:00 | Dunker, K (Indiana) | |
| Intrinsic disorder and protein function | Sem 1 | |
| Thursday 24 June | ||
| 09:30-10:30 | Ten Wolde, P, Paulsson, JM (Amsterdam, Cambridge) | |
| Thinking about gene regulatory networks | Sem 1 | |
| Tuesday 29 June | ||
| 09:30-10:30 | Laskey, R (MRC Cambridg) | |
| Maintenance and propagation of the blueprint for life Cancer and why DNA matters | Sem 2 | |
| 10:30-11:30 | Bell, S (MRC Cambridge) | |
| Maintenance and propagation of the blueprint for life The nuts and bolts of DNA replication | Sem 2 | |
| 11:45-12:45 | Venkitaraman, A (MRC Cambridge) | |
| Maintenance and propagation of the blueprint for life TBA | Sem 2 | |
| 13:45-14:45 | Downs, J (Cambridge) | |
| Maintenance and propagation of the blueprint for life Packaging of DNA and the problems it presents | Sem 2 | |
| Monday 05 July | ||
| 14:30-15:30 | McLeish, T (Leeds) | |
| Informal short blackboard talks on work in progress during the programme | Sem 2 | |
| Wednesday 07 July | ||
| 09:30-10:30 | Possee, B (Oxford) | |
| Baculovirus polyhedrin protein crystallisation in vivo: armour plating for viruses | Sem 1 | |
| 10:30-11:30 | Casey, R (Norwich) | |
| Protein crystallization in vivo: Seed proteins | Sem 1 | |
| 12:00-12:30 | Doye, J (Cambridge) | |
| Protein crystallization in vivo: The Why and Why not | Sem 1 | |
| Other Seminars |
|
Seminars in the University National and International Scientific Research Meetings |