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Appropriate macroscopic behaviour of the immune system, from distributed microscopic feedback

Date: 
Monday 10th December 2001 - 10:00 to 11:00
Venue: 
INI Seminar Room 1
Session Title: 
Immunology, Ecology and Epidemiology (main themes)
Abstract: 
Arguments are given for the tenet that the immune system can usefully be regarded as having short term goals -- which typically overlap and are often contradictory. Diverse sensors can measure how far the system is from its various goals. Simple models illustrate how distributed feedbacks based on sensory information can (i) harmonize conflicting goals, (ii) improve the performance of a given type of effector cell, (iii) cause the preferential amplification of more potent effectors.
University of Cambridge Research Councils UK
    Clay Mathematics Institute London Mathematical Society NM Rothschild and Sons