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Exploring Treespace

Date: 
Monday 20th June 2011 - 16:10 to 16:30
Venue: 
INI Seminar Room 1
Abstract: 
Phylogenies, or evolutionary histories, play a central role in modern biology, illustrating the interrelationships between species, and also aiding the prediction of structural, physiological, and biochemical properties. The reconstruction of the underlying evolutionary history from a set of morphological characters or biomolecular sequences is difficult since the optimality criteria favored by biologists are NP-hard, and the space of possible answers is huge. The number of possible phylogenetic trees for n taxa is (2n − 5)!!. Due to the hardness and the large number of possible answers, clever searching techniques and heuristics are used to estimate the underlying tree. We explore the underlying space of trees, under different metrics, in particular the nearest-neighbor-interchange (NNI), subtree-prune-and-regraft (SPR), tree-bisection-and-reconnection (TBR), and Robinson-Foulds (RF) distances.
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Presentation Material: 
University of Cambridge Research Councils UK
    Clay Mathematics Institute London Mathematical Society NM Rothschild and Sons