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Application of model-based designs in drug development

Presented by: 
S Leonov GlaxoSmithKline
Date: 
Tuesday 16th August 2011 - 15:30 to 16:00
Venue: 
INI Seminar Room 1
Abstract: 
We discuss the use of optimal model-based designs at different stages of drug development. Special attention is given to adaptive model-based designs in dose finding studies and designs for nonlinear mixed models which arise in population pharmacokinetic/pharmacodynamic studies. Examples of software tools and their application are provided
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Presentation Material: 
University of Cambridge Research Councils UK
    Clay Mathematics Institute London Mathematical Society NM Rothschild and Sons