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Importance of Standardising Genome-Scale Stoichiometric Models

Date: 
Tuesday 4th November 2014 - 11:15 to 11:30
Venue: 
INI Seminar Room 1
Abstract: 
Co-author: Orkun Soyer (University of Warwick)

Genome-scale stoichiometric model based approaches are increasingly being used for studying cellular metabolism, which has resulted in the development of stoichiometric models for a verity of organisms and cell types. However, many of these models vary significantly in terms of their syntax, chemical/reaction naming conventions, data structures, etc., mostly due to the use of different tools/methods for developing them. These variations often make the models incompatible; therefore, comparison/integration of multiple models become very difficult. In this talk I discuss about certain issues related to the lack of a common standard and emphasis the importance of standardising stoichiometric models.

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University of Cambridge Research Councils UK
    Clay Mathematics Institute London Mathematical Society NM Rothschild and Sons