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Principles of single and collective cancer cell migration: Impact by environmental substrate guidance

Presented by: 
Katarina Wolf Radboud Universiteit Nijmegen
Date: 
Thursday 10th December 2015 - 09:00 to 10:00
Venue: 
INI Seminar Room 1
Abstract: 
The migration of single cells or cell collectives in the multicellular organism is a complex process that takes place during a wide range of physiological functions in the organism, as well as during disease, such as cancer. Cell migration takes mainly place within complex extracellular matrix (ECM) environments of different dimensionality, structure, and spacing. Hence basic concepts on cell migration have been extended from 2D into the 3D context. Examples will be shown on how mesenchymal, amoeboid or collective migration modes are maintained or modulated by the tissue architecture in vitro as well as in vivo.
University of Cambridge Research Councils UK
    Clay Mathematics Institute London Mathematical Society NM Rothschild and Sons