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Aspects of bacterial persistence

Presented by: 
Stefan Klumpp
Thursday 21st January 2016 - 15:30 to 16:15
INI Seminar Room 1
Bacterial persistence is probably the best-established example of a system where noisy gene expression provides a fitness benefit. By inducing switching between two phenotypes, one well-adapted to growth-promoting conditions and one adapted to survival in hostile conditions, noise allows provides a mechanism that allows a population to deal with unpredictable environmental conditions. In the talk I will discuss the gene circuits and feedback underlying persistence, aspects of the evolution of these circuits as well as how such heterogeneity of the population can be advantageous for the spreading of a population in space.

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University of Cambridge Research Councils UK
    Clay Mathematics Institute London Mathematical Society NM Rothschild and Sons