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Structure, Mechanics, and Thermodynamics of Mixtures of Microtubules and Molecular Motors

Presented by: 
Daniel Joseph Needleman Harvard University
Date: 
Tuesday 14th May 2019 - 09:00 to 09:40
Venue: 
INI Seminar Room 1
Abstract: 
The self-organization of the microtubule cytoskeleton underlies diverse cell biological processes, ranging from chromosome segregation to neuronal morphogenesis. In order to gain insight into these biological processes, and the properties of active matter more generally, we are studying the large-scale structure, mechanics, and thermodynamics of collections of microtubules and molecular motors in cell extracts and reconstituted systems of purified components. I will present our recent work characterizing spontaneous contractions, ordering, instabilities, and heat production in these systems.
University of Cambridge Research Councils UK
    Clay Mathematics Institute London Mathematical Society NM Rothschild and Sons