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Modelling virus infections in the context of cancer therapies (and other diseases)

Presented by: 
Raluca Eftimie
Date: 
Tuesday 7th July 2020 - 14:30 to 15:00
Venue: 
INI Seminar Room 2
Abstract: 
Over the past years oncolytic viruses have generated much interest in cancer therapy, mainly due to the fact that once a virus is injected into the patient it can actively search for cancer cells and destroy them. However, the anti-tumour effect of oncolytic viruses is greatly diminished by anti-viral immune responses (both innate and adaptive responses), as well as by physical barriers inside the tumour. 
Using various single-scale and multi-scale mathematical modelling approaches, we will investigate the delicate balance between anti-viral and anti-tumour immune responses in the context of virus-tumour-immune interactions.





University of Cambridge Research Councils UK
    Clay Mathematics Institute London Mathematical Society NM Rothschild and Sons