Mathematical, statistical and computational aspects of the new science of metagenomics
MTG
24 March 2014 to 17 April 2014
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Programme theme
Metagenomics is the study of the total genomic content of microbial communities. In metagenomic studies, DNA material is sampled collectively from the microorganisms that populate the environment of interest (e.g. agricultural soil, ocean water, or the human gut). The extracted DNA sequences are subsequently used to profile the environment and its biodiversity, its dominant microbial classes or biological functions, and whether and how this profile differs from those of other environments.
The impact of metagenomics in our understanding of the natural world has been, and will continue to be, revolutionary and profound. Insights derived from metagenomic studies have become increasingly relevant in areas as diverse as human health, bioenergy, environmental sciences and paleontology.
This research programme will bring together leading expertise in the multiple disciplines involved in metagenomics including mathematics, computer science, probability and statistics, biomedical research and biology.
The brief of the programme will be to explore the major current analytical and computational open problems in metagenomics, and to identify opportunities for application and development of theory and methods, with an emphasis on synergy between disciplines.
Particular themes will include:
- Community profiling and comparative metagenomics
- Assembly of metagenomic data in the context of evolving NGS platforms
- Community structure and dynamics: beyond taxonomic and functional characterisation
- Analysis of microbial community transcriptomes, proteomes and metabolomes
These themes provide a rich source of mathematical problems in areas such as probability and statistics theory, dynamic programming, combinatorics and graph theory.
Click here to download the programme's final scientific report
Workshops
Mathematical, statistical and computational aspects of the new science of metagenomics
24 March 2014 to 28 March 2014
Evaluation workshop of the first CAMI challenge
10 May 2016 to 13 May 2016
Seminars
| Monday 24th March 2014 | |||
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| 10:15 to 11:15 | No Room Required | ||
| 11:15 to 11:25 | No Room Required | ||
| 11:25 to 11:30 | No Room Required | ||
| 12:30 to 13:45 | No Room Required | ||
| 14:45 to 15:30 | No Room Required | ||
| 15:30 to 16:15 | Room 1 | 
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| 16:15 to 17:00 | Room 1 |
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| 17:00 to 18:00 | No Room Required | ||
| Tuesday 25th March 2014 | |||
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| 10:30 to 11:00 | No Room Required | ||
| 11:00 to 11:45 |
Estimating within-host viral genetic diversity from next-generation sequencing data |
Room 1 |
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| 11:45 to 12:30 |
Metagenomic assembly and characterisation of viral signatures with MetaCortex |
Room 1 |
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| 12:30 to 13:45 | No Room Required | ||
| 13:45 to 14:45 | Room 1 |
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| 14:45 to 15:30 | No Room Required | ||
| 15:30 to 16:15 |
Species identification from medical metagenomic sequence data |
Room 1 |
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| 16:15 to 17:00 | Room 1 |
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| Wednesday 26th March 2014 | |||
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| 09:30 to 10:30 |
Understanding Biology from the Sequence Data of Uncultured Organisms |
Room 1 |
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| 10:30 to 11:00 | No Room Required | ||
| 11:00 to 11:45 |
Predictability and unpredictability in the dynamics of nutrient-cycling microbial ecosystems |
Room 1 |
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| 12:30 to 13:45 | No Room Required | ||
| 15:00 to 15:45 | No Room Required | ||
| 15:45 to 16:30 | Room 1 |
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| 16:30 to 17:00 | Room 1 |
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| 19:30 to 22:30 |
Conference Dinner at Cambridge Union Society hosted by Cambridge Dining Company |
No Room Required | |
| Thursday 27th March 2014 | |||
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| 09:30 to 10:30 |
Inferring genotype-phenotype relationships from (meta-)genomes |
Room 1 |
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| 10:30 to 11:00 | No Room Required | ||
| 11:45 to 12:30 | Room 1 |
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| 12:30 to 13:45 | No Room Required | ||
| 13:45 to 14:15 |
Quikr: Rapid Bacterial Community Reconstruction Via Compressive Sensing |
Room 1 |
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| 14:15 to 14:45 | Room 1 |
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| 14:45 to 15:15 |
Webserver-supported storage of metagenomic datasets using MEGANv5 |
Room 1 |
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| 15:15 to 16:00 | No Room Required | ||
| 16:00 to 16:30 | Room 1 |
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| 16:30 to 17:30 | Room 1 | ||
| Friday 28th March 2014 | |||
|---|---|---|---|
| 09:30 to 10:15 |
Microbiome, Metagenomics and High-dimensional Compositional Data Analysis |
Room 1 |
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| 10:15 to 11:00 | No Room Required | ||
| 11:00 to 11:45 |
Statistical Machine Learning for Modeling Early Respiratory Microbiota Composition |
Room 1 |
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| 11:00 to 11:45 |
Statistical Machine Learning for Modeling Early Respiratory Microbiota Composition |
Room 1 |
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| 11:00 to 11:45 |
Statistical Machine Learning for Modeling Early Respiratory Microbiota Composition |
Room 1 |
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| 12:30 to 13:45 | No Room Required | ||
| 13:45 to 14:30 |
Linking taxa to function through contig clustering of microbial metagenomes |
Room 1 |
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| 14:30 to 15:00 | Room 1 |
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| 15:00 to 15:45 | No Room Required | ||
| Sunday 30th March 2014 | |||
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| 09:00 to 17:00 | Discussion Room | ||
| Monday 31st March 2014 | |||
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| 09:00 to 17:00 | Discussion Room | ||
| Tuesday 1st April 2014 | |||
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| 15:00 to 16:00 |
Modelling macroecological patterns: Neutral theory and beyond |
Room 2 |
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| Wednesday 2nd April 2014 | |||
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| 15:00 to 16:30 | Room 1 |
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| Thursday 3rd April 2014 | |||
|---|---|---|---|
| 14:00 to 17:00 | Discussion Room | ||
| Friday 4th April 2014 | |||
|---|---|---|---|
| 09:30 to 12:30 | Room 1 | ||
| 14:00 to 17:00 | Discussion Room | ||
| Wednesday 9th April 2014 | |||
|---|---|---|---|
| 15:00 to 17:00 | Discussion Room | ||
| Friday 11th April 2014 | |||
|---|---|---|---|
| 14:00 to 17:00 | Discussion Room | ||
| Monday 14th April 2014 | |||
|---|---|---|---|
| 11:00 to 12:00 | Room 2 | ||
| 14:00 to 12:00 | Discussion Room | ||
| 14:40 to 15:00 | Room 1 | ||
| 15:00 to 15:20 |
The Oil Field Microbiome - How can Metagenomics Help the Oil Industry? |
Room 1 |
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| 15:40 to 16:00 | Room 1 |
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| 16:00 to 16:20 | Room 1 | ||
| 17:00 to 12:30 | Room 1 | ||
| Wednesday 16th April 2014 | |||
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| 10:30 to 12:00 | Room 1 | ||
| 13:00 to 14:00 | Discussion Room | ||
| Thursday 17th April 2014 | |||
|---|---|---|---|
| 09:00 to 11:00 | Discussion Room | ||
| 14:00 to 17:00 | Discussion Room | ||
| Wednesday 17th September 2014 | |||
|---|---|---|---|
| 15:00 to 17:00 | Room 2 | ||
Organisers
- Wally Gilks University of Leeds
- Daniel Huson Eberhard Karls Universität Tübingen
- Elisa Loza Rothamsted Research
- Simon Tavaré University of Cambridge
- Gabriel Valiente Technical University of Catalonia
- Tandy Warnow Japan Atomic Energy Agency & University of Texas at Austin
Supported By
