Protein interactions in vitro and in vivo
SMCW03
21 June 2004 to 23 June 2004
Workshop theme
Diagrams of proteins
On the left-hand side is a conventional diagram, as widely used in molecular biology, of adenylate kinase, where the chain of amino acids is drawn by loops, with cylinders for the alpha helices. On the right-hand side is a diagram of a simple, `physicists's' model of a protein, where the protein is taken to be cubic and where the differences in binding strengths of the different faces are denoted by different colours.
The purpose of this workshop is to bring together biologists and physicists working on protein-protein interactions, including aggregation and crystallisation.
Most of the dry mass of cells is protein, and proteins do most of the `work' in cells. Understanding their function is therefore essential to understand cells. The function of globular proteins requires specific and often very strong interactions, e.g. for recognition, in a complex mixture of thousands of other proteins. The proteins must also fold, be soluble, and avoid binding to other proteins, DNA, etc.
The workshop will bring together scientists from the physical and biological sciences to study how this feat is accomplished. Topics will include protein crystallisation and aggregation, protein interaction networks, macromolecular crowding, and related issues.
It will include a poster session where participants may present and discuss their work with scientist from theoretical physicists to structural biologists.
Timetable
| Monday 21st June 2004 | |||
|---|---|---|---|
| 13:30 to 14:30 |
Christopher Dobson University of Cambridge |
Room 1 | |
| 14:30 to 15:30 |
Anthony Fink University of California |
Room 1 | |
| 16:00 to 17:00 | Room 1 | ||
| Tuesday 22nd June 2004 | |||
|---|---|---|---|
| 09:00 to 10:00 |
Janet Thornton |
Room 1 | |
| 10:00 to 11:00 |
Michael Deem Rice University |
Room 1 | |
| 11:30 to 12:30 |
Sarah Teichmann University of Cambridge |
Room 1 | |
| 14:00 to 15:00 |
Joel Janin CNRS - Ecole Normale Superieure Paris |
Room 1 | |
| 16:00 to 17:00 |
Thomas Truskett |
Room 1 | |
| Wednesday 23rd June 2004 | |||
|---|---|---|---|
| 09:00 to 10:00 |
James Harden Johns Hopkins University |
Room 1 | |
| 10:00 to 11:00 |
Peter Vekilov University of Houston |
Room 1 | |
| 11:15 to 12:15 |
Laurence Pearl Institute of Cancer Research (ICR) |
Room 1 | |
Supported By
