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DNA in confined geometries: topology effects

Thursday 6th September 2012 - 13:30 to 14:10
INI Seminar Room 1
DNA can be found in confined geometries in different situations: for examples in viruses, in the chromosome or in artificial structures like in microfluidic devices. It is therefore interesting to study the statistical properties of the DNA depending on its length, concentration and topology. We present here data on circular DNA deposited in 2 dimensions with different concentration up to the overlap concentration c* and study also the effect of the length of the circular DNA. We characterize the statistical properties by determining the end-to-end distance as a function of the contour length, the directional correlation function, the area covered by the plasmids, the shape parameters like the sphericity as a function of the concentration.
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University of Cambridge Research Councils UK
    Clay Mathematics Institute London Mathematical Society NM Rothschild and Sons