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Streaming in Dd and Cell-cell adhesions

Presented by: 
John Dallon
Friday 18th September 2015 - 16:15 to 17:00
INI Seminar Room 1
Results from two mathematical models will be discussed. In the first, contradictions between experiments and modeling in Dictyostelium discoideum will be addressed. Experiments suggest that streaming in early aggregation is dependent on localization of certain proteins (ACA) in the cell. Yet mathematical modeling seems to contradict this result. In the second model, the role of cadherin motion in the cell membrane will be studied to determine how it affects cell-cell adhesion lengths. Using the immersed boundary method, the cell membrane and cortex is modeled. The model is used to help determine what role the actin cytoskeleton plays in cell-cell adhesion.
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University of Cambridge Research Councils UK
    Clay Mathematics Institute London Mathematical Society NM Rothschild and Sons